FP812CONTRIBUTION OF POPULATION PHARMACOKINETICS TO GUIDE GANCICLOVIR/VALGANCICLOVIR DOSAGE IN KIDNEY TRANSPLANT PATIENTS
نویسندگان
چکیده
منابع مشابه
Effect of Ganciclovir on Pharmacokinetics of Mycophenolic Mofetil, in Kidney Transplant Patients
ObjectiveMycophenolate mofetil (MMF) is commonly administered concomitantly with ganciclovir for managingtransplant recipients who infected with CMV. This study was conducted to evaluate the probable effects ofganciclovir on Mycophenolic acid (MPA) pharmacokinetic.Materials and MethodsTen kidney transplant recipients who full field inclusion and exclusion criterias enrolled in this study. Thefi...
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OBJECTIVES The aims of this study were to develop a population pharmacokinetic model of tacrolimus in adult kidney transplant recipients, to use this model to compare cytochrome P450 3A5 (CYP3A5) genotype-based initial dosing of tacrolimus with standard per-kilogram-based dosing, and to predict the best starting dose of tacrolimus based on patient genotype to achieve a trough concentration betw...
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To assess the influence of cyclosporin A (CsA) and tacrolimus (FK506) on mycophenolic acid (MPA) and correlation analysis of the pharmacokinetic parameters and patient characteristics, clinical outcome in Chinese kidney transplant recipients, the pharmacokinetics of 1000 mg mycophenolate mofetil (MMF) twice daily was measured by high-performance liquid chromatography (HPLC). PKS (Pharmaceutical...
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BACKGROUND AND OBJECTIVE Everolimus is a novel macrolide immunosuppressant used in the prevention of acute and chronic rejection of solid organ transplants. Everolimus is being actively investigated worldwide as a non-nephrotoxic alternative for calcineurin inhibitors. Its highly variable pharmacokinetics and narrow therapeutic window make it difficult to maintain an adequate exposure to preven...
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ژورنال
عنوان ژورنال: Nephrology Dialysis Transplantation
سال: 2015
ISSN: 1460-2385,0931-0509
DOI: 10.1093/ndt/gfv185.01